SSRIs and other antidepressants
Prozac®, Zoloft®, Paxil®, Luvox®, Celexa®, Effexor®, Wellbutrin®, and other antidepressants.

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file icon Psychiatric drug-induced Chronic Brain Impairment (CBI) 01/27/2012
Psychiatric drug-induced Chronic Brain Impairment (CBI): Implications for longterm treatment with psychiatric medication. International Journal of Risk & Safety in Medicine, 23: 193-200.
 
Peter R. Breggin, MD
 
Abstract: Understanding the hazards associated with long-term exposure to psychiatric drugs is very important but rarely emphasized in the scientific literature and clinical practice. Drawing on the scientific literature and clinical experience, the author describes the syndrome of Chronic Brain Impairment (CBM) which can be caused by any trauma to the brain including Traumatic Brain Injury (TBI), electroconvulsive therapy (ECT), and long-term exposure to psychiatric medications. Knowledge of the syndrome should enable clinicians to more easily identify long-term adverse effects caused by psychiatric drugs while enabling researchers to approach the problem with a more comprehensive understanding of the common elements of brain injury as they are manifested after long-term exposure to psychiatric medications. Treatment options are also discussed.
file icon Psychopharmacology and human values 05/15/1989
file icon Speech to FDA Panel, 2 Feb 2004 01/12/1995
SSRIs produce a continuum of stimulation that includes manic-like reactions, agitated depression, obsessive preoccupations, and akathisia.
file icon Antidepressant-Induced Suicide, Violence, and Mania: Risks for Military Personnel 02/11/2011

Ethical Human Psychology and Psychiatry, Volume 12, Number 2, 2010.


Peter R. Breggin, MD


The newer antidepressants frequently cause suicide, violence, and manic-like symptoms of activation or overstimulation, presenting serious hazards to active-duty soldiers who carry weapons under stressful conditions. These antidepressant-induced symptoms of activation can mimic posttraumatic stress disorder and are likely to worsen this common disorder in soldiers, increasing the hazard when they are prescribed to military personnel. Antidepressants should not be prescribed to soldiers during or after deployment.

file icon From Prozac to Ecstasy: the implication of new evidence for drug-induced brain damage 01/15/1991
An editorial appearing in vol 3 no 1 of the journal Ethical Human Sciences and Services in which Dr. Breggin points out that the kind of research used to justify a ban on MDMA (the recreational drug Ecstasy) could also be used to justify a ban of SSRI antidepressants.
file icon Copy of Breggin's Paxil product liability report in the Lacuzong case 01/12/2004
Report filed with the court stating Dr. Breggin's belief that Paxil induced Reynaldo Lacuzong to commit murder.
file icon Violence and suicide caused by antidepressants: report to the FDA 01/15/1994
A report Dr. Breggin presented to the FDA in August 2004 detailing the relation of suicidality and violence to antidepressants
file icon Antidepressant-induced suicidality and violence: more about deception than science 01/15/1993
Report presented at the September 14, 2004 press conference sponsored by the Alliance for Human Research Protection (AHRP) at the FDA Public Hearing on Antidepressants and Suicide.
file icon Letter to British Medical Journal re. Eli Lilly Documents 01/12/1996
A letter to the British Medical Journal in which Dr. Breggin notes Eli Lilly Prozac documents now in the possession of BMJ were disclosed in the early 1990s.
file icon Observations on SSRI-Induced Behavioral and Mental Abnormalities in Children and Adults 12/12/1993
Report to the FDA stressing mental and behavioral risks associated with SSRIs.
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WARNING!

Most psychiatric drugs can cause withdrawal reactions, sometimes including life-threatening emotional and physical withdrawal problems. In short, it is not only dangerous to start taking psychiatric drugs, it can also be dangerous to stop them. Withdrawal from psychiatric drugs should be done carefully under experienced clinical supervision. Methods for safely withdrawing from psychiatric drugs are discussed in Dr. Breggin's new book, Psychiatric Drug Withdrawal: A Guide for Prescribers, Therapists, Patients, and Their Families.