SSRIs and other antidepressants
Prozac®, Zoloft®, Paxil®, Luvox®, Celexa®, Effexor®, Wellbutrin®, and other antidepressants.
Psychiatric drug-induced Chronic Brain Impairment (CBI): Implications for longterm treatment with psychiatric medication. International Journal of Risk & Safety in Medicine, 23: 193-200.
Peter R. Breggin, MD
Abstract: Understanding the hazards associated with long-term exposure
to psychiatric drugs is very important but rarely emphasized in the
scientific literature and clinical practice. Drawing on the scientific
literature and clinical experience, the author describes the syndrome of
Chronic Brain Impairment (CBM) which can be caused by any trauma to the
brain including Traumatic Brain Injury (TBI), electroconvulsive therapy
(ECT), and long-term exposure to psychiatric medications. Knowledge of
the syndrome should enable clinicians to more easily identify long-term
adverse effects caused by psychiatric drugs while enabling researchers
to approach the problem with a more comprehensive understanding of the
common elements of brain injury as they are manifested after long-term
exposure to psychiatric medications. Treatment options are also
SSRIs produce a continuum of stimulation that includes manic-like reactions, agitated depression, obsessive preoccupations, and akathisia.
Ethical Human Psychology and Psychiatry, Volume 12, Number 2, 2010.
Peter R. Breggin, MD
The newer antidepressants frequently cause suicide, violence, and manic-like symptoms of activation or overstimulation, presenting serious hazards to active-duty soldiers who carry weapons under stressful conditions. These antidepressant-induced symptoms of activation can mimic posttraumatic stress disorder and are likely to worsen this common disorder in soldiers, increasing the hazard when they are prescribed to military personnel. Antidepressants should not be prescribed to soldiers during or after deployment.
An editorial appearing in vol 3 no 1 of the journal Ethical Human Sciences and Services in which Dr. Breggin points out that the kind of research used to justify a ban on MDMA (the recreational drug Ecstasy) could also be used to justify a ban of SSRI antidepressants.
Report filed with the court stating Dr. Breggin's belief that Paxil induced Reynaldo Lacuzong to commit murder.
A report Dr. Breggin presented to the FDA in August 2004 detailing the relation of suicidality and violence to antidepressants
Report presented at the September 14, 2004 press conference sponsored by the Alliance for Human Research Protection (AHRP) at the FDA Public Hearing on Antidepressants and Suicide.
A letter to the British Medical Journal in which Dr. Breggin notes Eli Lilly Prozac documents now in the possession of BMJ were disclosed in the early 1990s.
Report to the FDA stressing mental and behavioral risks associated with SSRIs.