Neuroleptics or antipsychotic drugs
Thorazine® , Trilafon®, Zyprexa®, Risperdal®, Geodon®, Seroquel®, Abilify®, and other antipsychotic medications
Breggin, PR. (2016). Rational Principles of Psychopharmacology for Therapists, Healthcare Providers and Clients. J Contemp Psychother 46:1–13.
Because the epidemic dispensing of psychiatric drugs is based on misinformation, it is important for all health professionals, consumers, and most citizens (including patients and their family members) to have a more rational understanding of how psychiatric drugs actually “work.” Instead of enforcing authoritarian “medication compliance” in obedience to the prescriber’s orders, informed therapists and healthcare providers have an ethical duty to provide scientific information about the real effects of psychiatric drugs. Instead of naively accepting whatever the doctor prescribes to them, consumers need to educate themselves about all medications, but especially about psychiatric ones, which are consistently misrepresented and oversold.
Psychiatric drug-induced Chronic Brain Impairment (CBI): Implications for longterm treatment with psychiatric medication. International Journal of Risk & Safety in Medicine, 23: 193-200.
Peter R. Breggin, MD
Abstract: Understanding the hazards associated with long-term exposure
to psychiatric drugs is very important but rarely emphasized in the
scientific literature and clinical practice. Drawing on the scientific
literature and clinical experience, the author describes the syndrome of
Chronic Brain Impairment (CBM) which can be caused by any trauma to the
brain including Traumatic Brain Injury (TBI), electroconvulsive therapy
(ECT), and long-term exposure to psychiatric medications. Knowledge of
the syndrome should enable clinicians to more easily identify long-term
adverse effects caused by psychiatric drugs while enabling researchers
to approach the problem with a more comprehensive understanding of the
common elements of brain injury as they are manifested after long-term
exposure to psychiatric medications. Treatment options are also
"Intoxication Anosognosia: The Spellbinding Effect of Psychiatric Drugs", Ethical Human Psychology and Psychiatry, 8, 201-215, 2006.
ABSTRACT: Why do so many individuals persist in taking psychoactive substances, including psychiatric drugs, after adverse mental and behavioral effects have become severe and even disabling? The author has previously proposed the brain-disabling principle of psychiatric treatment that all somatic psychiatric treatments impair the function of the brain and mind. Intoxication anosognosia (medication spellbinding) is an expression of this druginduced mental disability. Intoxication anosognosia causes the victim to underestimate the degree of drug-induced mental impairment, to deny the harmful role that the drug plays in the person’s altered state, and in many cases compel the individual to mistakenly believe that he or she is functioning better. In the extreme, the individual displays out-of-character compulsively destructive behaviors, including violence toward self and others.
Long-term neuroleptic use tied to tardive dykinesia.
"Parallels between Neuroleptic Effects and Lethargic Encephalitis: The Production of Dyskinesias and Cognitive Disorders," Brain and Cognition 23 (1993).
A sample chapter from Dr. Breggin's 1997 book Brain-Disabling Treatments in Psychiatry.
"Brain damage, dementia, and persistent cognitive dysfunction associated with neuroleptic drugs: evidence, etiology, implications." Journal of Mind and Behavior
11 (1990) 425-464.